New PDF release: Basic Aspects of Catechol-O-Methyltransferase and the

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  • December 29, 2017
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By Erkki Nissinen

ISBN-10: 0123813263

ISBN-13: 9780123813268

quantity ninety five of International assessment of Neurobiology specializes in Catechol-O-methyltransferase inhibition, and its medical software when it comes to Parkinson’s illness. Chapters hide COMT gene and proteins, L-dopa remedy in Parkinson’s sickness, the newest learn on COMT inhibitors and their scientific functions, in addition to destiny clients for his or her use.

  • Up-to-date precis of biochemistry and pharmacology of COMT and its inhibitors
  • Preclinical versions in COMT inhibitor devlopment
  • Transgenic COMT mice – newest info summarized
  • Chemistry of COMT inhibitors and their layout with molecular modelling
  • COMT gene and its rules and relation to dopamine similar diseases
  • Role of cofactor SAM rules in terms of homocysteine
  • Nonclinical and scientific defense of COMT inhibitors summarized
  • Future clients of COMT inhibitors in Parkinson’s disease

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Basic Aspects of Catechol-O-Methyltransferase and the Clinical Applications of its Inhibitors: 95 (International Review of Neurobiology) by Erkki Nissinen


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