New PDF release: Biophysics of Computation: Information Processing in Single

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  • December 30, 2017
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By Christof Koch

ISBN-10: 0195104919

ISBN-13: 9780195104912

ISBN-10: 0195181999

ISBN-13: 9780195181999

Neural community examine frequently builds at the fiction that neurons are easy linear threshold devices, thoroughly neglecting the hugely dynamic and intricate nature of synapses, dendrites, and voltage-dependent ionic currents. Biophysics of Computation: details Processing in unmarried Neurons demanding situations this concept, utilizing richly particular experimental and theoretical findings from mobile biophysics to give an explanation for the repertoire of computational services to be had to unmarried neurons. the writer indicates how person nerve cells can multiply, combine, or hold up synaptic inputs and the way details could be encoded within the voltage around the membrane, within the intracellular calcium focus, or within the timing of person spikes.
Key subject matters lined comprise the linear cable equation; cable conception as utilized to passive dendritic timber and dendritic spines; chemical and electric synapses and the way to regard them from a computational perspective; nonlinear interactions of synaptic enter in passive and lively dendritic bushes; the Hodgkin-Huxley version of motion strength new release and propagation; part area research; linking stochastic ionic channels to membrane-dependent currents; calcium- and potassium-currents and their function in details processing; the function of diffusion, buffering and binding of calcium, and different messenger structures in info processing and garage; brief- and long term types of synaptic plasticity; simplified types of unmarried cells; stochastic facets of neuronal firing; the character of the neuronal code; and unconventional versions of sub-cellular computation.
Biophysics of Computation: info Processing in unmarried Neurons serves as an amazing textual content for complex undergraduate and graduate classes in mobile biophysics, computational neuroscience, and neural networks, and should attract scholars and pros in neuroscience, electric and laptop engineering, and physics.

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Biophysics of Computation: Information Processing in Single Neurons (Computational Neuroscience Series) by Christof Koch

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