By Charles G. Cochrane,Michael A. Gimbrone
This quantity offers an research of the structure-function relationships of receptors. it's transparent that the constitution of receptors presents the preliminary information for varied features of every cellphone within the organism. via an research of the submolecular positive aspects of the receptors which are liable for the initiation of task of numerous biochemical pathways in the cells, a molecular knowing of the all vital preliminary, guiding occasions of mobile features will emerge. within the huge experience of cells interested by irritation, this contains mitogenesis, gene transcription, iteration of lipid metabolites and oxidants, clearance of molecules from the encompassing medium, and free up of granular components from cytoplasmic vesicles into the exterior medium, between others.
The contents of this primary quantity will function a origin for the topic of the second one quantity, that is sign transduction. 4 extra volumes are in instruction, together with Endothelial Leukocyte-Adhesion Molecules, Leukocyte Adhesive Mechanisms in irritation and Immunity, a moment quantity on sign Transduction, and Stimulation of Inflammatory Cells.
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Additional info for Cellular and Molecular Mechanisms of Inflammation: Receptors of Inflammatory Cells: Structure—Function Relationships: 1
Cellular and Molecular Mechanisms of Inflammation: Receptors of Inflammatory Cells: Structure—Function Relationships: 1 by Charles G. Cochrane,Michael A. Gimbrone